STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slit_1653PFAM: nitrogen regulatory protein P-II; KEGG: tmz:Tmz1t_1760 nitrogen regulatory protein P-II; Belongs to the P(II) protein family. (112 aa)    
Predicted Functional Partners:
Slit_0066
KEGG: dar:Daro_0054 ammonium transporter; TIGRFAM: ammonium transporter; PFAM: ammonium transporter.
 
 0.992
Slit_1085
PFAM: ammonium transporter; KEGG: rme:Rmet_4750 Rh-like protein/ammonium transporter.
 
 0.990
Slit_2925
KEGG: mei:Msip34_2494 signal transduction histidine kinase, nitrogen specific, NtrB; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein.
  
 0.975
glnD
UTP-GlnB uridylyltransferase, GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
 
 
 0.968
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
    
 
 0.839
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
     
 0.828
Slit_0832
ADP-ribosyl-(dinitrogen reductase) hydrolase; TIGRFAM: ADP-ribosyl-[dinitrogen reductase] hydrolase; KEGG: dar:Daro_1447 ADP-ribosylation/crystallin J1; PFAM: ADP-ribosylation/Crystallin J1.
    
 
 0.679
Slit_1655
PFAM: protein of unknown function DUF195; KEGG: mei:Msip34_1733 protein of unknown function DUF195.
       0.668
Slit_1656
PFAM: dienelactone hydrolase; KEGG: nmu:Nmul_A0914 dienelactone hydrolase.
       0.622
Slit_0098
KEGG: tgr:Tgr7_2259 hypothetical protein.
    
 
 0.593
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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