Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_1656PFAM: dienelactone hydrolase; KEGG: nmu:Nmul_A0914 dienelactone hydrolase. (263 aa)    
Predicted Functional Partners:
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
    0.725
Slit_1655
PFAM: protein of unknown function DUF195; KEGG: mei:Msip34_1733 protein of unknown function DUF195.
       0.718
Slit_2157
KEGG: nmu:Nmul_A0912 hypothetical protein.
 
  
 0.696
Slit_1653
PFAM: nitrogen regulatory protein P-II; KEGG: tmz:Tmz1t_1760 nitrogen regulatory protein P-II; Belongs to the P(II) protein family.
       0.622
Slit_1657
TIGRFAM: GTP-binding protein TypA; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain protein; KEGG: tbd:Tbd_0772 GTP-binding protein TypA; SMART: elongation factor G domain protein.
       0.538
Slit_1652
PFAM: type IV pilus assembly PilZ; KEGG: tmz:Tmz1t_0639 type IV pilus assembly PilZ.
       0.469
Slit_1658
TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; histidine kinase HAMP region domain protein; PAS fold domain protein; KEGG: tcx:Tcr_1222 diguanylate cyclase/phosphodiesterase; SMART: GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein; histidine kinase HAMP region domain protein.
       0.403
Slit_1659
TIGRFAM: phosphonate ABC transporter, periplasmic phosphonate-binding protein; KEGG: mgm:Mmc1_1819 phosphonate-binding periplasmic protein.
       0.403
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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