Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_1657TIGRFAM: GTP-binding protein TypA; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain protein; KEGG: tbd:Tbd_0772 GTP-binding protein TypA; SMART: elongation factor G domain protein. (610 aa)    
Predicted Functional Partners:
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.724
tsf
Translation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.
 
  
 0.615
Slit_0742
Ribonuclease BN; KEGG: nmu:Nmul_A0452 ribonuclease BN, putative; TIGRFAM: ribonuclease BN; PFAM: ribonuclease BN.
      0.610
rimP
Protein of unknown function DUF150; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.
  
  
 0.583
ychF
GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
  
  
 0.583
Slit_1658
TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; histidine kinase HAMP region domain protein; PAS fold domain protein; KEGG: tcx:Tcr_1222 diguanylate cyclase/phosphodiesterase; SMART: GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein; histidine kinase HAMP region domain protein.
       0.574
Slit_1659
TIGRFAM: phosphonate ABC transporter, periplasmic phosphonate-binding protein; KEGG: mgm:Mmc1_1819 phosphonate-binding periplasmic protein.
       0.574
rpmI
Ribosomal protein L35; KEGG: har:HEAR1799 50S ribosomal subunit protein A; TIGRFAM: ribosomal protein L35; PFAM: ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.
 
    0.569
rpsI
PFAM: ribosomal protein S9; KEGG: nmu:Nmul_A0560 30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
   
    0.566
trmD
tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
  
  
 0.547
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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