Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_1659TIGRFAM: phosphonate ABC transporter, periplasmic phosphonate-binding protein; KEGG: mgm:Mmc1_1819 phosphonate-binding periplasmic protein. (298 aa)    
Predicted Functional Partners:
Slit_1658
TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; histidine kinase HAMP region domain protein; PAS fold domain protein; KEGG: tcx:Tcr_1222 diguanylate cyclase/phosphodiesterase; SMART: GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein; histidine kinase HAMP region domain protein.
     
 0.780
Slit_2972
KEGG: gsu:GSU3438 hypothetical protein; TIGRFAM: alkylphosphonate utilization operon protein PhnA; PFAM: PhnA protein.
     
 0.666
Slit_0078
KEGG: mei:Msip34_0951 UreA carboxylase-associated protein 2; TIGRFAM: urea carboxylase-associated protein 2; PFAM: Domain of unknown function DUF1989.
      
 0.618
Slit_0081
KEGG: nmu:Nmul_A0944 allophanate hydrolase; TIGRFAM: allophanate hydrolase; PFAM: Amidase.
      
 0.618
Slit_1657
TIGRFAM: GTP-binding protein TypA; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain protein; KEGG: tbd:Tbd_0772 GTP-binding protein TypA; SMART: elongation factor G domain protein.
       0.574
Slit_1183
TIGRFAM: phosphonate ABC transporter, periplasmic phosphonate-binding protein; KEGG: mgm:Mmc1_3535 phosphonate ABC transporter, periplasmic phosphonate-binding protein.
  
   
0.469
Slit_0926
KEGG: azo:azo1131 hypothetical protein.
  
     0.461
Slit_1160
KEGG: mgm:Mmc1_3164 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein.
  
  
 0.434
Slit_0837
KEGG: azo:azo0523 nitrogen fixation protein; TIGRFAM: nitrogenase cofactor biosynthesis protein NifB; PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis protein; Radical SAM domain protein.
  
    0.421
Slit_0585
Multi-sensor hybrid histidine kinase; KEGG: pin:Ping_2140 fused multi-sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-4 domain protein; histidine kinase A domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; PAS domain containing protein; histidine kinase A domain protein; Hpt domain protein.
  
  
 0.411
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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