Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_1669SMART: Ankyrin; KEGG: tbd:Tbd_2728 hypothetical protein. (190 aa)    
Predicted Functional Partners:
Slit_0914
Ankyrin; KEGG: afr:AFE_1502 ankyrin repeat protein/rhodanese-like domain protein; PFAM: Ankyrin; SMART: Ankyrin.
  
     0.773
Slit_1670
KEGG: afw:Anae109_0587 hypothetical protein.
       0.723
Slit_1165
PFAM: Ankyrin; KEGG: pmx:PERMA_0372 ankyrin domain protein.
  
     0.662
Slit_1667
KEGG: tbd:Tbd_0133 hypothetical protein.
       0.651
Slit_1668
KEGG: tbd:Tbd_0132 hypothetical protein.
       0.651
Slit_1671
PFAM: ferredoxin; Oxidoreductase FAD-binding domain protein; KEGG: tbd:Tbd_1770 putative flavodoxin oxidoreductase.
   
 
 0.634
Slit_1678
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: tbd:Tbd_2477 putative glutamate synthase (NADPH) small subunit.
 
 
   0.519
Slit_1540
KEGG: net:Neut_1809 histone deacetylase superfamily protein; PFAM: histone deacetylase superfamily.
  
 
 0.505
cysG
uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
       0.462
Slit_1673
KEGG: tbd:Tbd_2342 hypothetical protein.
       0.462
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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