Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_1673KEGG: tbd:Tbd_2342 hypothetical protein. (200 aa)    
Predicted Functional Partners:
cysG
uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
       0.809
cbiA
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
       0.773
Slit_1675
PFAM: Polysulphide reductase NrfD; KEGG: vok:COSY_0784 intracellular sulfur oxidation protein DsrP.
       0.727
Slit_1676
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: tbd:Tbd_2475 iron-sulfur cluster protein.
       0.727
Slit_1677
KEGG: tbd:Tbd_2476 hypothetical protein.
       0.727
Slit_1678
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: tbd:Tbd_2477 putative glutamate synthase (NADPH) small subunit.
       0.727
Slit_1679
PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: tbd:Tbd_2478 reductase, iron-sulfur binding subunit, putative.
       0.698
Slit_1680
PFAM: Nitrate reductase gamma subunit; KEGG: tbd:Tbd_2479 putative DsrM protein.
       0.698
Slit_1681
KEGG: tgr:Tgr7_2190 sulfur relay protein, TusE/DsrC/DsvC family; TIGRFAM: sulfur relay protein, TusE/DsrC/DsvC family; PFAM: DsrC family protein.
       0.624
Slit_1671
PFAM: ferredoxin; Oxidoreductase FAD-binding domain protein; KEGG: tbd:Tbd_1770 putative flavodoxin oxidoreductase.
       0.605
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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