Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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cbiACobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (489 aa)    
Predicted Functional Partners:
cysG
uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
  
 0.965
Slit_2399
KEGG: bcj:BCAL3286 cobalamin adenosyltransferase protein; TIGRFAM: ATP/cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family.
 
  
 0.927
Slit_1680
PFAM: Nitrate reductase gamma subunit; KEGG: tbd:Tbd_2479 putative DsrM protein.
 
     0.886
Slit_1677
KEGG: tbd:Tbd_2476 hypothetical protein.
 
   
 0.884
Slit_1675
PFAM: Polysulphide reductase NrfD; KEGG: vok:COSY_0784 intracellular sulfur oxidation protein DsrP.
 
   
 0.879
Slit_1679
PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: tbd:Tbd_2478 reductase, iron-sulfur binding subunit, putative.
 
     0.862
Slit_1685
TIGRFAM: sulfite reductase, dissimilatory-type beta subunit; KEGG: tbd:Tbd_2484 sulfite reductase, dissimilatory-type beta subunit; PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein.
 
   
 0.862
Slit_1686
TIGRFAM: sulfite reductase, dissimilatory-type alpha subunit; KEGG: tbd:Tbd_2485 sulfite reductase, dissimilatory-type alpha subunit; PFAM: nitrite and sulphite reductase 4Fe-4S region.
 
   
 0.848
cobD
Cobalamin biosynthesis protein CbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
  
 0.843
Slit_1678
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: tbd:Tbd_2477 putative glutamate synthase (NADPH) small subunit.
 
   
 0.802
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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