Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
satTIGRFAM: sulfate adenylyltransferase; KEGG: tgr:Tgr7_0353 sulfate adenylyltransferase; PFAM: ATP-sulfurylase; Belongs to the sulfate adenylyltransferase family. (404 aa)    
Predicted Functional Partners:
Slit_1715
Adenylylsulfate reductase, alpha subunit; KEGG: tgr:Tgr7_0350 adenylylsulfate reductase; TIGRFAM: adenylylsulfate reductase, alpha subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein.
 
 
 0.987
Slit_1714
KEGG: tgr:Tgr7_0351 adenylylsulfate reductase, beta subunit; TIGRFAM: adenylylsulfate reductase, beta subunit; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein.
 
  
 0.986
Slit_1034
TIGRFAM: sulfate adenylyltransferase, small subunit; KEGG: nmu:Nmul_A1148 sulfate adenylyltransferase subunit 2; PFAM: phosphoadenosine phosphosulfate reductase.
  
 
 0.956
cysG
uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
 
  
 0.954
Slit_1711
PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: tgr:Tgr7_0340 putative molybdopterin oxidoreductase family protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
    
 0.947
Slit_1710
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: tgr:Tgr7_0339 putative iron-sulfur cluster-binding protein.
    
 0.941
Slit_1709
PFAM: DMSO reductase anchor subunit (DmsC); KEGG: tgr:Tgr7_0338 hypothetical protein.
    
  0.938
cysN
Sulfate adenylyltransferase, large subunit; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
    
 0.908
Slit_1697
KEGG: tbd:Tbd_0918 diheme cytochrome SoxA (sulfur oxidation).
     
 0.903
Slit_1698
PFAM: Sulphur oxidation protein SoxZ; KEGG: tbd:Tbd_0565 sulfur compound chelating protein SoxZ.
     
 0.903
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
Server load: low (12%) [HD]