Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_1725Metallophosphoesterase; KEGG: tgr:Tgr7_0341 phosphodiesterase, MJ0936 family; manually curated; PFAM: metallophosphoesterase. (174 aa)    
Predicted Functional Partners:
Slit_1714
KEGG: tgr:Tgr7_0351 adenylylsulfate reductase, beta subunit; TIGRFAM: adenylylsulfate reductase, beta subunit; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein.
  
     0.661
Slit_1715
Adenylylsulfate reductase, alpha subunit; KEGG: tgr:Tgr7_0350 adenylylsulfate reductase; TIGRFAM: adenylylsulfate reductase, alpha subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein.
 
     0.620
Slit_1688
KEGG: mxa:MXAN_7265 CRISPR-associated Cas6 family protein; TIGRFAM: CRISPR-associated protein, Cas6-related; PFAM: CRISPR-associated protein Cas6-related.
  
     0.579
Slit_1675
PFAM: Polysulphide reductase NrfD; KEGG: vok:COSY_0784 intracellular sulfur oxidation protein DsrP.
  
     0.569
Slit_2677
Peroxiredoxin; KEGG: mfa:Mfla_1689 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Peroxiredoxin-like.
   
 
 0.543
Slit_0404
Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.537
Slit_1726
Signal transduction histidine kinase, nitrate/nitrite-specific, NarQ; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: tbd:Tbd_2463 GAF sensor signal transduction histidine kinase; SMART: ATP-binding region ATPase domain protein; GAF domain protein.
       0.423
Slit_1727
KEGG: tbd:Tbd_2464 two component LuxR family transcriptional regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.
       0.423
Slit_1692
KEGG: tbd:Tbd_2491 hypothetical protein.
  
     0.411
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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