Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
Slit_1740SMART: Tetratricopeptide repeat; KEGG: glo:Glov_1853 tetratricopeptide TPR_2 repeat protein. (269 aa)    
Predicted Functional Partners:
Slit_1741
PFAM: Mammalian cell entry related domain protein; KEGG: gur:Gura_1894 hypothetical protein.
   
   0.785
Slit_1739
Adenylate/guanylate cyclase with Chase sensor; KEGG: hha:Hhal_1889 putative adenylate/guanylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; CHASE2 domain protein; SMART: adenylyl cyclase class-3/4/guanylyl cyclase.
   
   0.779
Slit_1738
PFAM: protein of unknown function DUF140; KEGG: geo:Geob_2687 protein of unknown function DUF140.
       0.773
Slit_1742
Hypothetical protein; KEGG: gur:Gura_1895 ABC-type transport system involved in resistance to organic solvents ATPase component-like protein.
       0.767
htpG
ATP-binding region ATPase domain protein; Molecular chaperone. Has ATPase activity.
   
 0.650
Slit_0509
Putative signal transduction protein with EFhand domain; KEGG: reu:Reut_A3217 calcium-binding EF-hand; PFAM: EF-Hand domain; SMART: Calcium-binding EF-hand-containing protein.
    
 0.601
Slit_1540
KEGG: net:Neut_1809 histone deacetylase superfamily protein; PFAM: histone deacetylase superfamily.
    
  0.587
Slit_0670
Peptidyl-prolyl cis-trans isomerase cyclophilin type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
  
  0.580
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.580
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 0.569
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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