Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_1751Arylesterase; KEGG: mfa:Mfla_1250 arylesterase; PFAM: lipolytic protein G-D-S-L family. (202 aa)    
Predicted Functional Partners:
Slit_1748
PFAM: protein of unknown function DUF214; KEGG: nmu:Nmul_A0948 hypothetical protein.
 
 
   0.938
Slit_1750
KEGG: nmu:Nmul_A1972 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase.
 
 
   0.932
Slit_2169
PFAM: lipolytic protein G-D-S-L family; KEGG: nmc:NMC1592 putative lipase.
  
  
 
0.922
Slit_1752
PFAM: protein of unknown function DUF255; KEGG: tbd:Tbd_2727 hypothetical protein.
   
 
 0.821
Slit_1451
KEGG: geo:Geob_1618 NHL repeat containing protein; PFAM: Ig domain protein group 2 domain protein; Kelch repeat-containing protein; SMART: Ig domain protein group 2 domain protein; Kelch repeat-containing protein.
  
 
 0.729
Slit_1749
KEGG: pna:Pnap_4960 hypothetical protein.
       0.570
Slit_1743
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.
 
  
 0.418
Slit_0391
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: nmu:Nmul_A0735 short-chain dehydrogenase/reductase SDR.
 
    0.408
cysG
uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
     
 0.406
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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