STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slit_1763Hypothetical protein; KEGG: ote:Oter_1251 glycoside hydrolase family protein. (504 aa)    
Predicted Functional Partners:
Slit_0002
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.986
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 0.967
Slit_1536
KEGG: rpf:Rpic12D_1465 DNA polymerase III, delta prime subunit; TIGRFAM: DNA polymerase III, delta prime subunit.
   
 0.841
Slit_0830
KEGG: mei:Msip34_1607 DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein.
   
 0.807
Slit_1764
PFAM: AB-hydrolase associated lipase region; KEGG: tcu:Tcur_1997 AB-hydrolase associated lipase region.
       0.781
Slit_2343
KEGG: eba:ebA3896 hypothetical protein.
    
   0.727
Slit_1315
SMART: helicase c2; KEGG: nmu:Nmul_A1412 helicase C2.
   
 
 0.691
Slit_1762
PFAM: GMC oxidoreductase; glucose-methanol-choline oxidoreductase; KEGG: lbl:LBL_2806 flavoprotein.
       0.673
Slit_1505
single-stranded-DNA-specific exonuclease RecJ; KEGG: cvi:CV_2475 exodeoxyribonuclease VII; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1.
    
 
 0.570
Slit_1761
KEGG: xau:Xaut_0992 integral membrane sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver.
       0.538
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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