Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Slit_1770PFAM: cytochrome c class I; KEGG: tmz:Tmz1t_3728 cytochrome c class I. (109 aa)    
Predicted Functional Partners:
Slit_0019
PFAM: cytochrome c class I; KEGG: mei:Msip34_0374 cytochrome c class I.
  
     0.775
Slit_1353
KEGG: mei:Msip34_0374 cytochrome c class I; manually curated; PFAM: cytochrome c class I.
  
     0.775
Slit_2042
KEGG: mei:Msip34_0374 cytochrome c class I.
  
     0.775
Slit_2780
KEGG: mmb:Mmol_0398 cytochrome c class I.
  
     0.775
Slit_1122
Nitric-oxide reductase; KEGG: dar:Daro_3191 cytochrome c oxidase, subunit I; PFAM: cytochrome c oxidase subunit I; Belongs to the heme-copper respiratory oxidase family.
   
  
 0.733
Slit_0643
PFAM: Polysulphide reductase NrfD; KEGG: gme:Gmet_1812 polysulphide reductase, NrfD.
     
 0.618
Slit_1675
PFAM: Polysulphide reductase NrfD; KEGG: vok:COSY_0784 intracellular sulfur oxidation protein DsrP.
     
 0.618
ntrC
Nitrogen metabolism transcriptional regulator, NtrC, Fis Family; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.
      
 0.618
Slit_0703
PFAM: Rieske [2Fe-2S] iron-sulphur domain; KEGG: nmu:Nmul_A0233 Rieske (2Fe-2S) region.
  
     0.470
Slit_0342
PFAM: glycosyl transferase family 39; KEGG: dfe:Dfer_1293 glycosyl transferase family 39.
  
     0.443
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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