Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
Slit_1773PFAM: ROK family protein; KEGG: sfu:Sfum_0489 ROK family protein. (295 aa)    
Predicted Functional Partners:
Slit_2903
TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; KEGG: tgr:Tgr7_2079 mannose-1-phosphate guanylyltransferase (GDP); PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase.
    
 0.950
pgi
KEGG: tgr:Tgr7_0871 glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase (PGI); Belongs to the GPI family.
    
 0.939
pfp
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
    
 0.937
glmS
Glucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
 
 0.919
fbp
PFAM: Inositol phosphatase/fructose-16-bisphosphatase; KEGG: noc:Noc_0021 fructose-1,6-bisphosphatase.
     
  0.900
Slit_0103
PFAM: PTS system fructose subfamily IIA component; KEGG: mmb:Mmol_2160 PTS system fructose subfamily IIA component.
    
 0.832
Slit_1771
KEGG: avi:Avi_3785 stability protein StbE; TIGRFAM: addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system.
       0.572
Slit_1772
Prevent-host-death family protein; Antitoxin component of a type II toxin-antitoxin (TA) system.
       0.572
Slit_1774
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; KEGG: aha:AHA_3237 GGDEF domain-containing protein; SMART: GGDEF domain containing protein.
       0.523
aroK
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
     
 0.508
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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