Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_1783KEGG: signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; CBS domain containing protein. (442 aa)    
Predicted Functional Partners:
Slit_1782
KEGG: hna:Hneap_1427 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver.
 
 
 0.951
Slit_1299
KEGG: rfr:Rfer_1982 response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: response regulator receiver; SMART: response regulator receiver.
 
 0.915
Slit_1163
KEGG: mag:amb1840 response regulator; PFAM: response regulator receiver; SMART: response regulator receiver.
 
     0.907
Slit_2939
KEGG: app:CAP2UW1_3587 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver.
 
 
 
 0.815
Slit_1271
KEGG: dar:Daro_0438 protein kinase; PFAM: Serine/threonine-protein kinase-like domain; SMART: serine/threonine protein kinase.
 
      0.753
Slit_1301
KEGG: dar:Daro_0970 response regulator receiver; PFAM: response regulator receiver; metal-dependent phosphohydrolase HD sub domain; SMART: response regulator receiver; metal-dependent phosphohydrolase HD region.
 
 
 0.753
Slit_1160
KEGG: mgm:Mmc1_3164 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein.
 
 
0.738
Slit_0553
MCP methyltransferase, CheR-type; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
      0.651
Slit_2416
KEGG: app:CAP2UW1_0788 cyclic nucleotide-binding protein; PFAM: Serine/threonine-protein kinase-like domain; cyclic nucleotide-binding; SMART: cyclic nucleotide-binding.
 
  
 
 0.637
Slit_1330
TIGRFAM: PAS sensor protein; PFAM: metal-dependent phosphohydrolase HD sub domain; PAS fold domain protein; response regulator receiver; KEGG: cpo:COPRO5265_0032 sensory box protein; SMART: response regulator receiver; PAS domain containing protein; PAC repeat-containing protein; metal-dependent phosphohydrolase HD region.
 
 
 0.629
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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