Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_1789Conserved hypothetical protein; KEGG: kinetoplast-associated protein-like protein. (1009 aa)    
Predicted Functional Partners:
Slit_1608
PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; NADH dehydrogenase (ubiquinone) 24 kDa subunit; Soluble ligand binding domain; KEGG: dar:Daro_0979 NADH dehydrogenase.
    
   0.901
Slit_2237
PFAM: NmrA family protein; KEGG: pna:Pnap_0622 NmrA family protein.
  
   0.806
Slit_0132
PFAM: cytochrome c1; KEGG: pla:Plav_2244 cytochrome c1.
    
   0.800
Slit_0130
Ubiquinol-cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
    
   0.795
Slit_1896
KEGG: xfa:XF2318 hypothetical protein.
    
   0.723
nuoB
NADH-quinone oxidoreductase, B subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
    
   0.720
Slit_1076
NADH-quinone oxidoreductase, chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.
    
 
 0.711
Slit_1609
PFAM: NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; KEGG: azo:azo1413 hydrogen dehydrogenase, gamma subunit.
    
 
 0.711
Slit_2367
PFAM: peptidase M16 domain protein; KEGG: mei:Msip34_1921 peptidase M16 domain protein.
    
 
 0.707
Slit_2368
PFAM: peptidase M16 domain protein; KEGG: nmu:Nmul_A2737 peptidase M16-like; Belongs to the peptidase M16 family.
    
 
 0.707
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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