STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slit_1833Quinone oxidoreductase, YhdH/YhfP family; KEGG: dar:Daro_1202 zinc-containing alcohol dehydrogenase superfamily protein; TIGRFAM: quinone oxidoreductase, YhdH/YhfP family; PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein. (331 aa)    
Predicted Functional Partners:
Slit_1189
TIGRFAM: 2-methylcitrate synthase/citrate synthase II; KEGG: bgl:bglu_2g21700 citrate synthase; PFAM: Citrate synthase; Belongs to the citrate synthase family.
   
 0.909
Slit_1187
PFAM: AMP-dependent synthetase and ligase; KEGG: abo:ABO_1731 acetyl-CoA synthetase.
   
 
 0.905
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 
 0.905
Slit_1850
TIGRFAM: acetyl-CoA acetyltransferase; KEGG: neu:NE1527 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
    
 0.832
Slit_1834
2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
   
 
 0.787
Slit_1835
SMART: Transketolase central region; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; KEGG: nmu:Nmul_A0857 2-oxoglutarate dehydrogenase E1 component; PFAM: Transketolase central region; dehydrogenase E1 component.
     
 0.682
Slit_1836
TIGRFAM: citrate synthase I; KEGG: cvi:CV_1070 type II citrate synthase; PFAM: Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.659
Slit_1838
KEGG: cvi:CV_1068 succinate dehydrogenase iron-sulfur subunit; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
  
 0.641
Slit_1841
KEGG: azo:azo1549 succinate dehydrogenase; TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit; PFAM: succinate dehydrogenase cytochrome b subunit.
  
 
 0.637
Slit_1839
KEGG: nmu:Nmul_A0861 succinate dehydrogenase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; succinate dehydrogenase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
  
  
 0.610
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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