Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_1849KEGG: app:CAP2UW1_3061 putative lipoprotein transmembrane. (187 aa)    
Predicted Functional Partners:
Slit_1848
KEGG: pna:Pnap_2842 hypothetical protein.
       0.788
Slit_1850
TIGRFAM: acetyl-CoA acetyltransferase; KEGG: neu:NE1527 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
       0.572
Slit_1851
PFAM: protein of unknown function DUF86; KEGG: app:CAP2UW1_0718 protein of unknown function DUF86.
       0.540
Slit_1852
PFAM: DNA polymerase beta domain protein region; KEGG: app:CAP2UW1_0719 DNA polymerase beta domain protein region.
       0.540
Slit_1853
PFAM: glutathione-dependent formaldehyde-activating GFA; KEGG: bur:Bcep18194_A4872 glutathione-dependent formaldehyde-activating, GFA.
 
     0.527
Slit_1857
PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: rfr:Rfer_2706 membrane protein involved in aromatic hydrocarbon degradation.
 
     0.527
Slit_1847
Metal dependent phosphohydrolase; KEGG: reu:Reut_B4068 response regulator receiver; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region.
       0.488
Slit_1856
PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; Enoyl-CoA hydratase/isomerase; KEGG: nmu:Nmul_A0097 3-hydroxyacyl-CoA dehydrogenase, NAD-binding.
 
     0.448
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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