Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
Slit_1859PFAM: AMP-dependent synthetase and ligase; KEGG: neu:NE1549 AMP-dependent synthetase and ligase. (602 aa)    
Predicted Functional Partners:
Slit_1861
PFAM: Protein of unknown function DUF1974; acyl-CoA dehydrogenase domain protein; KEGG: nmu:Nmul_A0094 acyl-CoA dehydrogenase.
  
 0.909
Slit_1289
KEGG: tgr:Tgr7_0082 Hpt sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; Hpt domain protein.
     
  0.900
Slit_1858
PFAM: thioesterase superfamily protein; KEGG: bvi:Bcep1808_2816 thioesterase superfamily protein.
 
   0.842
Slit_1856
PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; Enoyl-CoA hydratase/isomerase; KEGG: nmu:Nmul_A0097 3-hydroxyacyl-CoA dehydrogenase, NAD-binding.
  
 
 0.756
Slit_1860
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: rmr:Rmar_2203 short-chain dehydrogenase/reductase SDR.
  
 
 0.731
Slit_2174
PFAM: acyl-CoA dehydrogenase domain protein; KEGG: ctt:CtCNB1_3363 acyl-CoA dehydrogenase-like protein.
  
 0.686
Slit_1857
PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: rfr:Rfer_2706 membrane protein involved in aromatic hydrocarbon degradation.
     
 0.613
rplE
Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
    
 
 0.549
rplR
Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
    
 
 0.545
Slit_1579
KEGG: ade:Adeh_2181 ABC branched-chain amino acid transporter, fused ATPase and inner-membrane subunits; PFAM: ABC transporter related; inner-membrane translocator; SMART: AAA ATPase; Belongs to the binding-protein-dependent transport system permease family.
  
  
 0.545
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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