Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_1860PFAM: short-chain dehydrogenase/reductase SDR; KEGG: rmr:Rmar_2203 short-chain dehydrogenase/reductase SDR. (272 aa)    
Predicted Functional Partners:
Slit_1861
PFAM: Protein of unknown function DUF1974; acyl-CoA dehydrogenase domain protein; KEGG: nmu:Nmul_A0094 acyl-CoA dehydrogenase.
  
 0.823
Slit_1856
PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; Enoyl-CoA hydratase/isomerase; KEGG: nmu:Nmul_A0097 3-hydroxyacyl-CoA dehydrogenase, NAD-binding.
  
 0.783
Slit_1859
PFAM: AMP-dependent synthetase and ligase; KEGG: neu:NE1549 AMP-dependent synthetase and ligase.
  
 
 0.731
Slit_1858
PFAM: thioesterase superfamily protein; KEGG: bvi:Bcep1808_2816 thioesterase superfamily protein.
  
 
 0.703
Slit_1857
PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: rfr:Rfer_2706 membrane protein involved in aromatic hydrocarbon degradation.
 
     0.581
Slit_1850
TIGRFAM: acetyl-CoA acetyltransferase; KEGG: neu:NE1527 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.545
Slit_1862
KEGG: ajs:Ajs_1333 hypothetical protein.
       0.526
Slit_0450
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+))., Phosphate acetyltransferase; KEGG: azo:azo3211 malic enzyme; PFAM: malic protein NAD-binding; malic protein domain protein; phosphate acetyl/butaryl transferase.
   
 
 0.476
Slit_2174
PFAM: acyl-CoA dehydrogenase domain protein; KEGG: ctt:CtCNB1_3363 acyl-CoA dehydrogenase-like protein.
 
 0.461
Slit_1160
KEGG: mgm:Mmc1_3164 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein.
    
 
 0.447
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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