Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_1862KEGG: ajs:Ajs_1333 hypothetical protein. (125 aa)    
Predicted Functional Partners:
Slit_1860
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: rmr:Rmar_2203 short-chain dehydrogenase/reductase SDR.
       0.526
Slit_1861
PFAM: Protein of unknown function DUF1974; acyl-CoA dehydrogenase domain protein; KEGG: nmu:Nmul_A0094 acyl-CoA dehydrogenase.
       0.526
Slit_1863
PFAM: outer membrane efflux protein; KEGG: dar:Daro_2263 outer membrane efflux protein.
       0.519
Slit_1864
KEGG: app:CAP2UW1_4655 hypothetical protein; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
       0.519
Slit_1865
KEGG: app:CAP2UW1_0150 heavy metal efflux pump, CzcA family; TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
       0.519
Slit_1866
KEGG: tbd:Tbd_1326 hypothetical protein.
       0.519
Slit_1858
PFAM: thioesterase superfamily protein; KEGG: bvi:Bcep1808_2816 thioesterase superfamily protein.
       0.470
Slit_1859
PFAM: AMP-dependent synthetase and ligase; KEGG: neu:NE1549 AMP-dependent synthetase and ligase.
       0.470
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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