STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slit_1970Efflux transporter, RND family, MFP subunit; KEGG: Cobalt-zinc-cadmium resistance protein czcB, putative; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (362 aa)    
Predicted Functional Partners:
Slit_1971
KEGG: mmb:Mmol_1762 heavy metal efflux pump, CzcA family; TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 0.969
Slit_1973
KEGG: dar:Daro_2803 outer membrane efflux protein.
 
 
 0.886
Slit_1865
KEGG: app:CAP2UW1_0150 heavy metal efflux pump, CzcA family; TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 0.832
Slit_1972
KEGG: bja:blr4113 hypothetical protein.
       0.774
Slit_1974
KEGG: rfr:Rfer_0192 hypothetical protein.
       0.773
Slit_1863
PFAM: outer membrane efflux protein; KEGG: dar:Daro_2263 outer membrane efflux protein.
 
 
 0.660
Slit_1975
KEGG: tgr:Tgr7_1532 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region.
       0.588
Slit_0934
PFAM: acriflavin resistance protein; KEGG: app:CAP2UW1_2665 acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 0.548
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
       0.520
Slit_1487
Outer membrane efflux protein; CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin). Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
 
 
 0.427
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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