Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nnrDCarbohydrate kinase, YjeF related protein; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. (302 aa)    
Predicted Functional Partners:
Slit_2027
KEGG: pat:Patl_0542 hypothetical protein.
       0.773
Slit_2028
PFAM: Spermine synthase; KEGG: azo:azo2053 putative spermidine synthase.
       0.773
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
       0.658
Slit_2029
KEGG: mfa:Mfla_1747 hypothetical protein.
       0.504
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
  
 0.466
Slit_1179
Protein of unknown function UPF0079; KEGG: nmu:Nmul_A2531 hypothetical protein; manually curated; PFAM: protein of unknown function UPF0079.
 
 
 0.422
Slit_0734
PFAM: heat shock protein Hsp20; KEGG: tbd:Tbd_2312 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family.
 
    0.414
Slit_1396
TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: ComEC/Rec2-related protein; KEGG: nmu:Nmul_A2506 DNA internalization-related competence protein ComEC/Rec2; SMART: beta-lactamase domain protein.
 
    0.407
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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