STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slit_2034PFAM: zinc/iron permease; KEGG: mei:Msip34_1703 zinc/iron permease. (257 aa)    
Predicted Functional Partners:
crcB
CrcB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
  
  
 0.817
rimO
MiaB-like tRNA modifying enzyme YliG; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.
       0.800
Slit_2030
PFAM: protein of unknown function DUF190; KEGG: tbd:Tbd_1037 hypothetical protein.
       0.773
Slit_2032
PFAM: protein of unknown function UPF0153; KEGG: tmz:Tmz1t_2001 protein of unknown function UPF0153.
  
    0.773
Slit_2035
KEGG: app:CAP2UW1_2066 methyl-accepting chemotaxis sensory transducer; PFAM: chemotaxis sensory transducer; type IV pilus assembly PilZ; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein.
       0.634
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 
    
 0.569
Slit_2768
PFAM: cytochrome c biogenesis protein transmembrane region; alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; KEGG: oca:OCAR_6268 cytochrome c biogenesis protein, transmembrane region.
  
    0.552
Slit_2312
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.523
Slit_0185
PFAM: NAD-dependent epimerase/dehydratase; domain of unknown function DUF1731; KEGG: mca:MCA0496 hypothetical protein.
  
    0.518
Slit_2037
PFAM: protein of unknown function DUF152; KEGG: mei:Msip34_1707 protein of unknown function DUF152; Belongs to the multicopper oxidase YfiH/RL5 family.
       0.486
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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