Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_2159KEGG: dac:Daci_4264 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region. (430 aa)    
Predicted Functional Partners:
Slit_1232
PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: maq:Maqu_0258 metal dependent phosphohydrolase.
  
     0.775
Slit_1847
Metal dependent phosphohydrolase; KEGG: reu:Reut_B4068 response regulator receiver; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region.
  
    0.775
Slit_2160
TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; CHASE domain protein; MASE1 domain protein; PAS fold domain protein; PAS fold-3 domain protein; KEGG: tgr:Tgr7_1851 diguanylate cyclase/phosphodiesterase with PAS/PAC and CHASE sensor(s); SMART: GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein.
 
 
 
 0.501
Slit_1559
TIGRFAM: diguanylate cyclase; PFAM: cyclic nucleotide-binding; GGDEF domain containing protein; KEGG: mgm:Mmc1_1387 cyclic nucleotide-binding protein; SMART: GGDEF domain containing protein.
  
   
 0.462
Slit_1545
Diguanylate cyclase with GAF sensor; SMART: GGDEF domain containing protein; GAF domain protein; TIGRFAM: diguanylate cyclase; KEGG: mms:mma_3133 hypothetical protein; PFAM: GGDEF domain containing protein.
  
 
   0.447
Slit_2624
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: hch:HCH_04724 response regulator; SMART: GGDEF domain containing protein.
  
 
   0.438
Slit_1314
Diguanylate cyclase; SMART: GGDEF domain containing protein; TIGRFAM: diguanylate cyclase; KEGG: azo:azo3777 GGDEF family protein; PFAM: GGDEF domain containing protein.
  
 
   0.420
Slit_0537
Metal dependent phosphohydrolase; KEGG: dar:Daro_3357 hypothetical protein; PFAM: GAF domain protein; metal-dependent phosphohydrolase HD sub domain; SMART: GAF domain protein; metal-dependent phosphohydrolase HD region.
 
  
 0.415
Slit_1560
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; Diverse 7TM receptor transmembrane region; Diverse 7TM receptor extracellular region 2; KEGG: tbd:Tbd_2693 diguanylate cyclase; SMART: GGDEF domain containing protein.
  
 
   0.408
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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