STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slit_2169PFAM: lipolytic protein G-D-S-L family; KEGG: nmc:NMC1592 putative lipase. (226 aa)    
Predicted Functional Partners:
Slit_1751
Arylesterase; KEGG: mfa:Mfla_1250 arylesterase; PFAM: lipolytic protein G-D-S-L family.
  
  
 
0.922
Slit_1748
PFAM: protein of unknown function DUF214; KEGG: nmu:Nmul_A0948 hypothetical protein.
 
 
   0.861
Slit_1750
KEGG: nmu:Nmul_A1972 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase.
 
 
   0.832
Slit_1451
KEGG: geo:Geob_1618 NHL repeat containing protein; PFAM: Ig domain protein group 2 domain protein; Kelch repeat-containing protein; SMART: Ig domain protein group 2 domain protein; Kelch repeat-containing protein.
  
 
 0.729
Slit_2168
Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: mag:amb3563 C4-dicarboxylate transport sensor protein DctB; SMART: ATP-binding region ATPase domain protein.
       0.512
Slit_0391
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: nmu:Nmul_A0735 short-chain dehydrogenase/reductase SDR.
 
    0.411
cysG
uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
     
 0.406
Slit_2170
TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; KEGG: rfr:Rfer_3654 diguanylate cyclase with PAS/PAC sensor; SMART: GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein.
       0.402
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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