Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
Slit_2215Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: rmr:Rmar_2228 multi-sensor signal transduction histidine kinase; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein. (485 aa)    
Predicted Functional Partners:
Slit_2214
KEGG: pol:Bpro_0709 two component LuxR family transcriptional regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.
 
 
 0.957
Slit_1160
KEGG: mgm:Mmc1_3164 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein.
  
 
 0.911
Slit_1821
KEGG: sfu:Sfum_1664 two component LuxR family transcriptional regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.
 
 
 0.834
Slit_0151
Two component transcriptional regulator, LuxR family; KEGG: mpt:Mpe_A3237 response regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.
 
 
 0.833
Slit_0622
KEGG: har:HEAR1863 LuxR family transcriptional regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.
 
 
 0.833
Slit_1593
KEGG: bph:Bphy_6558 two component LuxR family transcriptional regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.
 
 
 0.833
Slit_1727
KEGG: tbd:Tbd_2464 two component LuxR family transcriptional regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.
 
 
 0.833
Slit_2500
Two component transcriptional regulator, LuxR family; KEGG: rsk:RSKD131_3304 two-component response regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.
 
 
 0.833
Slit_2581
Two component transcriptional regulator, LuxR family; KEGG: mag:amb3889 response regulator; PFAM: regulatory protein LuxR; response regulator receiver; SMART: regulatory protein LuxR; response regulator receiver.
 
 
 0.833
Slit_1726
Signal transduction histidine kinase, nitrate/nitrite-specific, NarQ; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: tbd:Tbd_2463 GAF sensor signal transduction histidine kinase; SMART: ATP-binding region ATPase domain protein; GAF domain protein.
  
    0.776
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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