Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Slit_2220PFAM: protein of unknown function DUF498; KEGG: cvi:CV_0994 hypothetical protein. (122 aa)    
Predicted Functional Partners:
Slit_2221
PFAM: ATPase associated with various cellular activities AAA_3; KEGG: tgr:Tgr7_1491 MoxR protein, putative.
       0.768
Slit_2099
PFAM: Zinc finger, CHCC-type; KEGG: dar:Daro_3295 hypothetical protein.
  
     0.644
Slit_1632
PFAM: cyclase/dehydrase; KEGG: mei:Msip34_1230 cyclase/dehydrase.
  
     0.636
Slit_1403
PFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; KEGG: nmu:Nmul_A2416 hypothetical protein.
 
     0.620
Slit_2219
PFAM: aminotransferase class I and II; KEGG: rme:Rmet_1967 aminotransferase AlaT.
       0.611
Slit_0167
PFAM: protein of unknown function DUF185; KEGG: app:CAP2UW1_0267 protein of unknown function DUF185.
  
     0.605
Slit_2218
KEGG: azo:azo2081 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding.
       0.573
Slit_2398
PFAM: Domain of unknown function DUF1841; KEGG: nmu:Nmul_A2703 hypothetical protein.
  
     0.562
bioC
Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.
  
     0.536
Slit_0647
PFAM: Glutathione S-transferase domain; KEGG: nmu:Nmul_A1002 glutathione S-transferase-like protein; Belongs to the GST superfamily.
  
     0.475
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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