Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Slit_2221PFAM: ATPase associated with various cellular activities AAA_3; KEGG: tgr:Tgr7_1491 MoxR protein, putative. (305 aa)    
Predicted Functional Partners:
Slit_2223
KEGG: app:CAP2UW1_1368 transglutaminase domain protein; PFAM: transglutaminase domain protein; SMART: transglutaminase domain protein.
 
   
 0.868
Slit_2222
PFAM: protein of unknown function DUF58; KEGG: tmz:Tmz1t_3010 protein of unknown function DUF58.
  
 0.832
Slit_2220
PFAM: protein of unknown function DUF498; KEGG: cvi:CV_0994 hypothetical protein.
       0.768
Slit_0846
PFAM: protein of unknown function DUF58; KEGG: avn:Avin_18820 hypothetical protein.
 
  
 0.647
Slit_2541
Lysine decarboxylase; KEGG: mms:mma_1191 arginine decarboxylase; PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein.
    
 
 0.544
Slit_2219
PFAM: aminotransferase class I and II; KEGG: rme:Rmet_1967 aminotransferase AlaT.
       0.532
Slit_2218
KEGG: azo:azo2081 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding.
       0.522
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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