STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_2228Ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18. (145 aa)    
Predicted Functional Partners:
Slit_2229
PFAM: peptidase M22 glycoprotease; KEGG: net:Neut_1298 peptidase M22, glycoprotease.
 
 
 0.986
Slit_2227
Manually curated; TIGRFAM: phage SPO1 DNA polymerase-related protein; KEGG: nmu:Nmul_A2121 phage SPO1 DNA polymerase-related protein; PFAM: Uracil-DNA glycosylase superfamily.
  
    0.831
Slit_2226
TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; histidine kinase HAMP region domain protein; PAS fold domain protein; PAS fold-4 domain protein; KEGG: dar:Daro_4048 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); SMART: GGDEF domain containing protein; histidine kinase HAMP region domain protein; PAS domain containing protein; PAC repeat-containing protein.
       0.773
ispD
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
  
    0.579
ispF
2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
       0.578
Slit_2225
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; KEGG: azo:azo2059 REC/GGDEF-domain-containing protein; SMART: GGDEF domain containing protein; response regulator receiver.
       0.556
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.470
proS
prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]
 
     0.416
Slit_1541
CoA-binding domain protein; KEGG: nmu:Nmul_A1676 GCN5-related N-acetyltransferase; PFAM: CoA-binding domain protein; GCN5-related N-acetyltransferase; SMART: CoA-binding domain protein.
  
 
 0.413
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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