Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Slit_2279KEGG: azo:azo2552 twitching motility protein; TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E. (443 aa)    
Predicted Functional Partners:
Slit_2699
PFAM: Type II secretion system F domain; KEGG: mei:Msip34_0586 type II secretion system protein.
  
   
 0.776
Slit_2607
PFAM: Type II secretion system F domain; KEGG: har:HEAR1952 type IV pilus assembly protein TapC.
  
   
 0.761
Slit_0108
TIGRFAM: type IV pilus assembly protein PilM; KEGG: dar:Daro_0210 type IV pilus assembly protein PilM.
  
  
 0.755
Slit_2700
Prepilin peptidase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
  
   
 0.746
Slit_0684
PFAM: Type II secretion system F domain; KEGG: dar:Daro_3408 type II secretion system protein.
  
   
 0.743
Slit_1831
PFAM: Type II secretion system F domain; KEGG: tbd:Tbd_1294 type II secretion system protein F.
  
   
 0.715
Slit_0497
KEGG: cvi:CV_3812 general secretion pathway protein F; TIGRFAM: general secretion pathway protein F; PFAM: Type II secretion system F domain.
  
   
 0.684
Slit_0112
Type IV pilus secretin PilQ; KEGG: azo:azo3646 type 4 fimbrial biogenesis protein; TIGRFAM: type IV pilus secretin PilQ; PFAM: type II and III secretion system protein; NolW domain protein; Secretin/TonB short domain.
  
  
 0.614
Slit_2278
KEGG: hypothetical LOC100006405.
       0.590
Slit_0110
PFAM: Pilus assembly protein PilO; KEGG: neu:NE2314 putative fimbrial type-4 assembly membrane transmembrane protein.
  
  
 0.575
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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