Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_2288SMART: beta-lactamase domain protein; KEGG: nmu:Nmul_A1139 beta-lactamase-like. (254 aa)    
Predicted Functional Partners:
Slit_2289
Hypothetical protein; KEGG: rme:Rmet_1069 putative transmembrane protein.
       0.809
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
       0.799
Slit_2291
KEGG: cyn:Cyan7425_2808 FeoA family protein; PFAM: FeoA family protein; SMART: FeoA family protein.
       0.534
Slit_2292
Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
       0.534
Slit_0837
KEGG: azo:azo0523 nitrogen fixation protein; TIGRFAM: nitrogenase cofactor biosynthesis protein NifB; PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis protein; Radical SAM domain protein.
  
  
 0.498
Slit_1160
KEGG: mgm:Mmc1_3164 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein.
  
  
 0.455
Slit_1594
Multi-sensor signal transduction histidine kinase; SMART: ATP-binding region ATPase domain protein; PAC repeat-containing protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; GAF domain protein; TIGRFAM: PAS sensor protein; KEGG: bpy:Bphyt_6241 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; histidine kinase HAMP region domain protein; GAF domain protein; histidine kinase dimerisation and phosphoacceptor region.
  
  
 0.441
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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