STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slit_2297KEGG: cli:Clim_0691 rhodanese domain protein; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein. (154 aa)    
Predicted Functional Partners:
rlmD
RNA methyltransferase, TrmA family; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
       0.746
Slit_2299
PFAM: 3'-5' exonuclease, PolB-like; KEGG: nmu:Nmul_A2217 hypothetical protein.
       0.746
Slit_0143
KEGG: tgr:Tgr7_2218 rhodanese domain protein; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein.
  
     0.742
Slit_2415
KEGG: afr:AFE_2558 rhodanese-like domain protein; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein.
  
     0.684
ispF
2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
  
    0.447
Slit_2300
TIGRFAM: LexA repressor; KEGG: mei:Msip34_2108 LexA repressor; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S24 family.
       0.411
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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