STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slit_2300TIGRFAM: LexA repressor; KEGG: mei:Msip34_2108 LexA repressor; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S24 family. (198 aa)    
Predicted Functional Partners:
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.935
Slit_0830
KEGG: mei:Msip34_1607 DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein.
 
 
 0.886
Slit_1049
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
   
  
 0.612
Slit_2439
KEGG: lch:Lcho_4294 XRE family transcriptional regulator; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein.
     
 0.478
Slit_2301
KEGG: dar:Daro_2475 hypothetical protein.
  
    0.466
rlmD
RNA methyltransferase, TrmA family; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
  
  
 0.454
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
   
 0.451
Slit_2299
PFAM: 3'-5' exonuclease, PolB-like; KEGG: nmu:Nmul_A2217 hypothetical protein.
       0.423
Slit_2297
KEGG: cli:Clim_0691 rhodanese domain protein; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein.
       0.411
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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