Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Slit_2309PFAM: peptidase M48 Ste24p; KEGG: mmb:Mmol_1014 peptidase M48 Ste24p. (281 aa)    
Predicted Functional Partners:
Slit_2311
PFAM: CHASE2 domain protein; KEGG: mei:Msip34_1734 putative CHASE2 sensor protein.
 
     0.835
Slit_2310
PFAM: SH3 type 3 domain protein; KEGG: mei:Msip34_1735 SH3 type 3 domain protein.
       0.775
Slit_2312
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
       0.564
Slit_2621
PFAM: Peptidase M23; KEGG: nmu:Nmul_A1120 peptidase M23B.
 
 
   0.458
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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