Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
Experiments
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[Homology]
Score
Slit_2320Extracellular solute-binding protein family 3; KEGG: azo:azo0499 putative cyclohexadienyl dehydratase; PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; Belongs to the bacterial solute-binding protein 3 family. (266 aa)    
Predicted Functional Partners:
Slit_2321
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold domain protein; PAS fold-4 domain protein; GGDEF domain containing protein; KEGG: mmb:Mmol_0423 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein.
       0.773
Slit_2322
KEGG: oca:OCAR_5411 transcriptional regulator, ArsR family; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR.
       0.478
Slit_2323
PFAM: Activator of Hsp90 ATPase 1 family protein; KEGG: lil:LA3534 hypothetical protein.
       0.478
Slit_0880
NAD(+)--dinitrogen-reductase ADP-D-ribosyltransferase; KEGG: dar:Daro_1416 hypothetical protein; PFAM: Dinitrogenase reductase ADP-ribosyltransferase.
  
     0.453
Slit_1160
KEGG: mgm:Mmc1_3164 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein.
   
 
 0.417
Slit_2325
PFAM: bifunctional deaminase-reductase domain protein; KEGG: rfr:Rfer_2843 bifunctional deaminase-reductase-like.
  
    0.404
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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