Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Slit_2328PFAM: bifunctional deaminase-reductase domain protein; KEGG: stp:Strop_1085 deaminase-reductase domain-containing protein. (193 aa)    
Predicted Functional Partners:
Slit_2325
PFAM: bifunctional deaminase-reductase domain protein; KEGG: rfr:Rfer_2843 bifunctional deaminase-reductase-like.
 
     0.899
Slit_2327
PFAM: Activator of Hsp90 ATPase 1 family protein; KEGG: oca:OCAR_5415 activator of HSP90 ATPase 1 family protein.
 
     0.862
Slit_2326
PFAM: Activator of Hsp90 ATPase 1 family protein; KEGG: mes:Meso_1126 activator of HSP90 ATPase-like protein.
 
     0.832
Slit_2323
PFAM: Activator of Hsp90 ATPase 1 family protein; KEGG: lil:LA3534 hypothetical protein.
 
     0.760
Slit_2324
Hypothetical protein; KEGG: aba:Acid345_3072 DGPFAETKE domain-containing protein.
 
     0.748
Slit_2322
KEGG: oca:OCAR_5411 transcriptional regulator, ArsR family; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR.
 
     0.712
Slit_2330
PFAM: 3-demethylubiquinone-9 3-methyltransferase; KEGG: rca:Rcas_4095 3-demethylubiquinone-9 3-methyltransferase.
 
     0.684
Slit_2332
PFAM: 3-demethylubiquinone-9 3-methyltransferase; KEGG: tbd:Tbd_1204 PhnB protein.
 
     0.596
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
  
 0.559
Slit_2331
PFAM: bifunctional deaminase-reductase domain protein; KEGG: dfe:Dfer_1353 bifunctional deaminase-reductase domain protein.
 
    
0.531
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.