Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_2349PFAM: protein of unknown function DUF1415; KEGG: lch:Lcho_2114 hypothetical protein. (189 aa)    
Predicted Functional Partners:
rhlE
DEAD/DEAH box helicase domain protein; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA.
       0.773
srkA
Aminoglycoside phosphotransferase; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
       0.545
Slit_2347
PFAM: histidine triad (HIT) protein; KEGG: pmx:PERMA_0670 protein hit.
       0.507
Slit_2286
KEGG: nmu:Nmul_A1143 cupin region; PFAM: Cupin 4 family protein; SMART: transcription factor jumonji jmjC domain protein.
  
     0.473
ychF
GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
       0.469
Slit_2346
KEGG: nmu:Nmul_A1106 hypothetical protein; Belongs to the UPF0225 family.
       0.424
Slit_2099
PFAM: Zinc finger, CHCC-type; KEGG: dar:Daro_3295 hypothetical protein.
  
     0.417
Slit_0975
KEGG: azo:azo3242 hypothetical protein.
  
     0.411
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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