Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Slit_2359KEGG: mfa:Mfla_0682 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase. (245 aa)    
Predicted Functional Partners:
Slit_2360
KEGG: nmu:Nmul_A0584 putative ABC-2 type transport system permease protein.
 
 
 0.980
Slit_2361
PFAM: ABC-type uncharacterised transport system; KEGG: nmu:Nmul_A0583 hypothetical protein.
 
   
 0.955
Slit_2514
PFAM: ABC-2 type transporter; KEGG: sfu:Sfum_2392 fis family transcriptional regulator.
 
  
 0.931
Slit_2515
PFAM: ABC-2 type transporter; KEGG: sfu:Sfum_2393 ABC-2 type transporter.
 
  
 0.931
Slit_2575
KEGG: mxa:MXAN_6402 ABC transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase.
 
    
0.923
mutM
formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
       0.812
Slit_0092
ABC transporter related protein; KEGG: bxe:Bxe_B1387 nitrate/sulfonate/bicarbonate ABC transporter ATPase; PFAM: ABC transporter related; SMART: AAA ATPase.
 
    
0.743
Slit_2079
KEGG: nmu:Nmul_A0951 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase.
 
    
0.704
lolD
Lipoprotein releasing system, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
 
    
0.629
potA
Spermidine/putrescine ABC transporter ATPase subunit; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
 
    
0.591
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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