Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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coaDPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (158 aa)    
Predicted Functional Partners:
Slit_2366
Methyltransferase; PFAM: Protein of unknown function methylase putative; manually curated; KEGG: cvi:CV_4202 hypothetical protein; TIGRFAM: methyltransferase.
 
  
 0.967
coaX
Transcriptional activator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
 
  
 0.954
Slit_0751
Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
 
 
 0.943
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
    
 0.937
Slit_2367
PFAM: peptidase M16 domain protein; KEGG: mei:Msip34_1921 peptidase M16 domain protein.
       0.813
Slit_2368
PFAM: peptidase M16 domain protein; KEGG: nmu:Nmul_A2737 peptidase M16-like; Belongs to the peptidase M16 family.
       0.809
Slit_2364
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: tgr:Tgr7_0299 4Fe-4S ferredoxin iron-sulfur binding domain protein.
     
 0.780
Slit_2906
Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
    
 0.724
Slit_2704
Thiamine monophosphate synthase; KEGG: mfa:Mfla_2230 hypothetical protein; manually curated; PFAM: thiamine monophosphate synthase; NUDIX hydrolase.
 
    0.625
Slit_2091
Riboflavin biosynthesis protein RibF; SMART: Riboflavin kinase; manually curated; TIGRFAM: riboflavin biosynthesis protein RibF; cytidyltransferase-related domain protein; KEGG: nmu:Nmul_A2653 riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; Belongs to the ribF family.
 
   
 0.601
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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