STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slit_2379PFAM: protein of unknown function DUF615; KEGG: net:Neut_0689 hypothetical protein; Belongs to the UPF0307 family. (173 aa)    
Predicted Functional Partners:
rpmG
KEGG: dar:Daro_3144 50S ribosomal protein L33; TIGRFAM: ribosomal protein L33; PFAM: ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.
    
   0.754
Slit_2038
Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
    
 
 0.754
Slit_2378
PFAM: peptidase U62 modulator of DNA gyrase; KEGG: nmu:Nmul_A2415 peptidase U62, modulator of DNA gyrase.
  
    0.644
rplD
Ribosomal protein L4/L1e; Forms part of the polypeptide exit tunnel.
  
 
   0.581
rplU
Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
   
   0.514
obg
GTP-binding protein Obg/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
    
 
 0.512
rpmF
KEGG: tbd:Tbd_1553 50S ribosomal protein L32; TIGRFAM: ribosomal protein L32; PFAM: ribosomal L32p protein; Belongs to the bacterial ribosomal protein bL32 family.
   
   0.511
rplM
Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
   
   0.510
rpmB
Ribosomal protein L28; Manually curated; TIGRFAM: ribosomal protein L28; KEGG: mei:Msip34_0335 ribosomal protein L28; PFAM: ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
    
   0.504
rplK
Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
    
   0.504
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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