STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slit_2407KEGG: nmu:Nmul_A1053 hypothetical protein. (133 aa)    
Predicted Functional Partners:
Slit_2405
RNA polymerase, sigma-24 subunit, ECF subfamily; KEGG: dar:Daro_3076 RNA polymerase factor sigma-70; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; Belongs to the sigma-70 factor family. ECF subfamily.
 
    0.961
Slit_2406
KEGG: nmu:Nmul_A1052 hypothetical protein.
       0.773
Slit_2524
Trehalose-phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
   
    0.723
Slit_2403
KEGG: mmb:Mmol_0617 acetolactate synthase, small subunit; TIGRFAM: acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein.
       0.603
Slit_2404
KEGG: nmu:Nmul_A0474 acetolactate synthase, large subunit, biosynthetic type; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region.
       0.579
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
       0.519
cobD
Cobalamin biosynthesis protein CbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
  
     0.494
Slit_0975
KEGG: azo:azo3242 hypothetical protein.
  
     0.461
Slit_0138
KEGG: har:HEAR0170 putative rod shape-determining protein MreD; TIGRFAM: rod shape-determining protein MreD; PFAM: Rod shape-determining protein MreD.
 
     0.455
Slit_0147
Putative phytochrome sensor protein; KEGG: dar:Daro_0193 hypothetical protein; PFAM: protein of unknown function DUF484; SMART: GAF domain protein.
  
     0.454
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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