Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_2414PFAM: SirA family protein; KEGG: tbd:Tbd_0574 hypothetical protein; Belongs to the sulfur carrier protein TusA family. (78 aa)    
Predicted Functional Partners:
Slit_0806
Cysteine desulfurase NifS; Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.
   
 0.958
iscS
Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
   
 0.958
Slit_1684
KEGG: tbd:Tbd_2483 DsrE protein; TIGRFAM: sulfur relay protein TusD/DsrE; PFAM: DsrE family protein.
  
 
 0.956
Slit_1707
PFAM: SirA family protein; KEGG: tbd:Tbd_0574 hypothetical protein; Belongs to the sulfur carrier protein TusA family.
  
  
 
0.905
Slit_1706
KEGG: afr:AFE_2556 hypothetical protein.
 
  
 0.820
Slit_2415
KEGG: afr:AFE_2558 rhodanese-like domain protein; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein.
  
  
 0.790
Slit_2416
KEGG: app:CAP2UW1_0788 cyclic nucleotide-binding protein; PFAM: Serine/threonine-protein kinase-like domain; cyclic nucleotide-binding; SMART: cyclic nucleotide-binding.
       0.689
Slit_2417
KEGG: nmu:Nmul_A2537 peptidase M48, Ste24p; manually curated; PFAM: peptidase M48 Ste24p.
       0.491
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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