Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Slit_2416KEGG: app:CAP2UW1_0788 cyclic nucleotide-binding protein; PFAM: Serine/threonine-protein kinase-like domain; cyclic nucleotide-binding; SMART: cyclic nucleotide-binding. (430 aa)    
Predicted Functional Partners:
Slit_0050
KEGG: app:CAP2UW1_3892 adenylate/guanylate cyclase; PFAM: Forkhead-associated protein; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: Forkhead-associated protein; adenylyl cyclase class-3/4/guanylyl cyclase.
 
 
 0.905
Slit_0531
PFAM: Protein phosphatase 2C-like; KEGG: dar:Daro_3360 protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein.
 0.899
Slit_0402
PFAM: Protein phosphatase 2C-like; KEGG: har:HEAR2127 putative serine/threonine specific protein phosphatase; SMART: protein phosphatase 2C domain protein.
 
 0.887
Slit_0532
FHA domain containing protein; KEGG: dar:Daro_3359 forkhead-associated; PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein.
 
 
 
 0.800
Slit_2415
KEGG: afr:AFE_2558 rhodanese-like domain protein; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein.
  
    0.690
Slit_2414
PFAM: SirA family protein; KEGG: tbd:Tbd_0574 hypothetical protein; Belongs to the sulfur carrier protein TusA family.
       0.689
Slit_1352
PFAM: protein of unknown function DUF323; KEGG: mag:amb1714 hypothetical protein.
 
    0.645
Slit_1783
KEGG: signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; CBS domain containing protein.
 
  
 
 0.637
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.626
Slit_1160
KEGG: mgm:Mmc1_3164 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein.
   
 
 0.544
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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