Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_2417KEGG: nmu:Nmul_A2537 peptidase M48, Ste24p; manually curated; PFAM: peptidase M48 Ste24p. (475 aa)    
Predicted Functional Partners:
Slit_2416
KEGG: app:CAP2UW1_0788 cyclic nucleotide-binding protein; PFAM: Serine/threonine-protein kinase-like domain; cyclic nucleotide-binding; SMART: cyclic nucleotide-binding.
       0.535
Slit_2621
PFAM: Peptidase M23; KEGG: nmu:Nmul_A1120 peptidase M23B.
 
 
   0.513
Slit_2415
KEGG: afr:AFE_2558 rhodanese-like domain protein; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein.
  
    0.499
Slit_2414
PFAM: SirA family protein; KEGG: tbd:Tbd_0574 hypothetical protein; Belongs to the sulfur carrier protein TusA family.
       0.491
Slit_1366
PFAM: MotA/TolQ/ExbB proton channel; KEGG: har:HEAR2492 putative biopolymer transport ExbB-like protein.
  
    0.445
Slit_2913
KEGG: tbd:Tbd_2697 type I secretion outer membrane protein, TolC; TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein.
  
     0.440
Slit_0935
KEGG: tbd:Tbd_2697 type I secretion outer membrane protein, TolC; TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein.
  
     0.438
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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