Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
Slit_2497Decaheme c-type cytochrome, DmsE family; KEGG: dar:Daro_1402 double CXXCH motif-containing protein; TIGRFAM: decaheme c-type cytochrome, DmsE family; cytochrome C family protein; PFAM: doubled CXXCH domain protein. (355 aa)    
Predicted Functional Partners:
Slit_2496
TIGRFAM: decaheme-associated outer membrane protein, MtrB/PioB family; KEGG: dar:Daro_1403 hypothetical protein.
   
 
 0.800
Slit_2498
PFAM: cytochrome c class I; KEGG: dar:Daro_1401 cytochrome c, class I.
 
     0.675
Slit_1160
KEGG: mgm:Mmc1_3164 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein.
    
 
 0.601
Slit_0585
Multi-sensor hybrid histidine kinase; KEGG: pin:Ping_2140 fused multi-sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-4 domain protein; histidine kinase A domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; PAS domain containing protein; histidine kinase A domain protein; Hpt domain protein.
    
 
 0.599
Slit_1289
KEGG: tgr:Tgr7_0082 Hpt sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; Hpt domain protein.
    
 
 0.599
Slit_2495
PFAM: NapC/NirT cytochrome c domain protein; KEGG: dar:Daro_2579 NapC/NirT cytochrome c, N-terminal.
     
 0.554
Slit_0160
PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; BFD domain protein [2Fe-2S]-binding domain protein; molybdopterin oxidoreductase Fe4S4 region; KEGG: hch:HCH_05823 anaerobic dehydrogenase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
  
 
 0.431
Slit_0641
Molybdopterin dinucleotide-binding region; KEGG: gur:Gura_2777 nitrate reductase; manually curated; PFAM: molydopterin dinucleotide-binding region; molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
 
 0.418
Slit_1711
PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: tgr:Tgr7_0340 putative molybdopterin oxidoreductase family protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
 
 0.418
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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