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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slit_2502PFAM: protein of unknown function DUF485; KEGG: cvi:CV_3280 hypothetical protein. (103 aa)    
Predicted Functional Partners:
Slit_2501
KEGG: mag:amb2727 symporter; TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
  
 0.990
Slit_2490
KEGG: pol:Bpro_4144 Na+/solute symporter; TIGRFAM: putative sodium symporter protein; PFAM: Na+/solute symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
  
 0.828
Slit_2504
KEGG: tbd:Tbd_0090 CBS signal-transduction protein; PFAM: protein of unknown function DUF294 nucleotidyltransferase putative; CBS domain containing protein; cyclic nucleotide-binding; Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding; SMART: CBS domain containing protein.
 
  
 0.815
Slit_2503
TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; KEGG: tbd:Tbd_0089 exonuclease; SMART: Exonuclease.
 
    0.805
Slit_1187
PFAM: AMP-dependent synthetase and ligase; KEGG: abo:ABO_1731 acetyl-CoA synthetase.
  
  
 0.483
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 0.483
Slit_0364
PFAM: AMP-dependent synthetase and ligase; KEGG: dar:Daro_4173 AMP-dependent synthetase and ligase.
  
  
 0.454
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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