Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Slit_2504KEGG: tbd:Tbd_0090 CBS signal-transduction protein; PFAM: protein of unknown function DUF294 nucleotidyltransferase putative; CBS domain containing protein; cyclic nucleotide-binding; Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding; SMART: CBS domain containing protein. (633 aa)    
Predicted Functional Partners:
Slit_2503
TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; KEGG: tbd:Tbd_0089 exonuclease; SMART: Exonuclease.
 
    0.982
Slit_2490
KEGG: pol:Bpro_4144 Na+/solute symporter; TIGRFAM: putative sodium symporter protein; PFAM: Na+/solute symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
  
 0.888
Slit_2501
KEGG: mag:amb2727 symporter; TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
  
 0.871
Slit_2502
PFAM: protein of unknown function DUF485; KEGG: cvi:CV_3280 hypothetical protein.
 
  
 0.827
Slit_2491
TIGRFAM: putative solute symporter protein; KEGG: app:CAP2UW1_3750 membrane protein.
 
     0.747
trpC
KEGG: azo:azo3322 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; Belongs to the TrpC family.
     
 0.517
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.488
Slit_0115
KEGG: mei:Msip34_2803 glutamate synthase (ferredoxin); PFAM: glutamate synthase; ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein.
     
 0.481
Slit_2489
Protein of unknown function DUF299; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
  
  
 0.411
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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