Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_2524Trehalose-phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose. (247 aa)    
Predicted Functional Partners:
Slit_2523
KEGG: rfr:Rfer_2163 alpha,alpha-trehalose-phosphate synthase (UDP-forming); PFAM: glycosyl transferase family 20.
 
 0.999
Slit_2525
PFAM: glycoside hydrolase 15-related; KEGG: glo:Glov_1816 glycoside hydrolase 15-related.
   
 0.982
Slit_2157
KEGG: nmu:Nmul_A0912 hypothetical protein.
   
    0.924
Slit_0436
RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
   
    0.792
Slit_2407
KEGG: nmu:Nmul_A1053 hypothetical protein.
   
    0.792
Slit_0713
Catalase; Has an organic peroxide-dependent peroxidase activity. Belongs to the catalase family.
  
  
 0.657
Slit_1450
KEGG: aeh:Mlg_2089 fructose-bisphosphate aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase.
   
    0.651
glgB
1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
  
 
 0.612
Slit_1343
PFAM: aldo/keto reductase; KEGG: ypb:YPTS_1101 aldo/keto reductase.
   
   0.590
Slit_1702
RNA polymerase, sigma-24 subunit, ECF subfamily; KEGG: tbd:Tbd_1836 sigma-24 (FecI); TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; Belongs to the sigma-70 factor family. ECF subfamily.
  
    0.460
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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