STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slit_2532PFAM: peptidase U32; KEGG: lhk:LHK_02651 probable collagenase. (649 aa)    
Predicted Functional Partners:
Slit_1608
PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; NADH dehydrogenase (ubiquinone) 24 kDa subunit; Soluble ligand binding domain; KEGG: dar:Daro_0979 NADH dehydrogenase.
    
   0.822
Slit_0582
PFAM: peptidase U32; KEGG: dar:Daro_0108 peptidase U32.
  
 
 0.560
fur
Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: mei:Msip34_1882 ferric uptake regulator, Fur family; Belongs to the Fur family.
       0.500
nuoC
NADH (or F420H2) dehydrogenase, subunit C; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family.
   
   0.436
Slit_2533
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold domain protein; histidine kinase HAMP region domain protein; GGDEF domain containing protein; KEGG: tcx:Tcr_1150 diguanylate cyclase/phosphodiesterase; SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein; histidine kinase HAMP region domain protein.
       0.436
Slit_2032
PFAM: protein of unknown function UPF0153; KEGG: tmz:Tmz1t_2001 protein of unknown function UPF0153.
  
     0.413
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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